Tyrant Mutation (Resident Evil 2)

After the Tyrant falls into the molten steel vat, the damage he receives is extreme. With its limiter destroyed, there's nothing stopping this Tyrant from undergoing a mutation to reveal its true self.

This time the Tyrant won't hold back, he will charge at you every chance he gets. The same tactics apply for the Tyrant at the end of the first game, just avoid him for a few minutes until a mysterious woman drops you a Rocket Launcher. Use this to finish it off once and for all.