Giant Spider (Resident Evil 2)

These spiders of awesome size were created when an ordinary arachnid was exposed to the leaked T-Virus. These venomous eight-legged monsters can surprise you when they suddenly land in front of you with their ability to walk on walls and ceilings, but their presence within a room can be known to you if you listen out for their low-bass thumping noise as the scurry around.

Despite their size they are surprisingly quick. Using the Shotgun or the Grenade Launcher are good choice when it comes to disposing of these and keeping them at bay.