An orange keycard.
This is used in Leon's Chapter 2 to unlock the security door at the bottom of the secret exit from the Cathedral.
Underground Keycard (Resident Evil 6)
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Location
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Leon - Chapter 2
Cathedral. Once you have acquired all four Madonna statues to open the secret passageway behind the dais in the main hall of the cathedral, a Lepotitsa will attack as you approach to leave. This keycard is on the body of the Lepotitsa once you defeat it.