Uroboros Albert Wesker (Resident Evil 5)

When Wesker's original superhuman abilities were weakened through an overdose of the drug PG67A/W, he took the Uroboros Virus into his own body in a last resort to defeat Chris and Sheva.

The Uroboros's characteristic tentacles have fused together onto both of his arms, and metal pieces of debris from the virus container have adhered to his right arm, making it an even more lethal killing weapon. Wesker unleashes the full power of the Uroboros Virus while still keeping it under complete control. His agility is not to be underestimated, and his power and endurance are completely beyond anything Chris and Sheva have faced before.