Zombies are the residents of Raccoon City who have become undead flesh-seekers given un-life through mutations and reanimation caused by the T-Virus. Zombies appear in many forms and dress styles in the game, and they are the most frequently encountered enemy. Even if you clear a room of zombies, you will find that areas respawn after a certain length of time, and zombies will follow you from room to room.
Crows are native black birds in Raccoon City area that have eaten contaminated flesh or have been attacked by contaminated rats to become infected with the T-Virus. Their infection gives them an intense hunger for living flesh. Crows tend to appear in flocks and attack as a group.
Scissor Worms are mutant insects that have grown long tails with twin razor-sharp piercing stingers, which the monsters use to inflict the POISON status on its victims. They appear in massive droves , flooding the streets of Raccoon City during the "Outbreak" scenario.
These creatures only appear in the Hard and Very Hard difficulty settings.
The giant moth is a unique enemy that appears in the underground laboratory in the "Below Freezing Point" scenario. Its attack methods include butting the character with its giant body to knock them down, and rapidly fluttering its wings to release a cloud of pollen that inflicts the POISON status.
Hunters are humanoid lizard-like creatures that scour areas looking for easy prey. With cat-like reflexes and instant strike capabilities, this is one monster that can go from zero to a hundred in an instant. Hunters can leap down long corridors and across large rooms to attack, and they tend to follow characters from room to room.
Small Leeches are ordinary blood-sucking parasites that have grown to double their normal size through Dr. James Marcus' genetic tampering. Small Leeches infest the Raccoon Hospital, travelling from corridor to corridor via the ventilation system, looking for fresh blood sources.
This is a giant leech that has made a home for itself in the basement of the Raccoon Hospital. It's massive size makes it slow but it has long tentacles and a mouth filled with razor sharp teeth to attack with should you get too close.
The key to defeating it is to keep your distance and use ranged weapons. In the middle of the section where you fight it there are explosive objects attached to the sides. Shooting these will inflict major damage to the Queen Leech.
Lickers are crouched humanoid creatures with extra long sharp talons that they use for attacking as well as crawling along walls and ceilings. Lickers are aptly named due to the super-strong tongue muscles they possess, which extends up to five feet. The tongue is used to pierce standing targets, causing high amounts of damage. The Licker's outer flesh resembles raw muscle tissue, giving the appearance that the creature has been turned inside out.
Zombie Dogs are stray hounds that roam the city looking for fresh, living meat to attack. Having lost their pack instinct during viral conversion, Zombie Dogs now appear alone and infrequently. They run as quickly as they did in life, and they attack by leaping off the ground to snap with their powerful jaws, or by grabbing a victim's leg and chewing on it mercilessly.
These mutated, overgrown web-spinners silently patrol the sewer waterways below Raccoon University, seeking to capture prey that stumbles into their lair. Giant Spiders can crawl on the walls and ceilings, and pour poisonous acid saliva onto their victims from above. They leap onto stationary targets and knock them to the ground, then administer a bite attack that also inflicts POISON status.
Giant Wasps cling to walls until they detect intruders within their domain. Then they take flight and attack mercilessly from the air, tackling player characters to the ground and stinging them with gigantic tail needles that inflict poison status.
This variant of the Hunter species is frog-like in appearance, and its attack habits indicate it was probably developed by genetically manipulating amphibians. These creatures in aquatic areas, and they have the ability to attack in water as well as on dry land. Because player characters cannot attack whilst in the water, this is where they become the most vulnerable to attack.
"Neptune" is the Umbrella code name for Great White Sharks that were experimented upon with the T-Virus. These mutated creatures now possess the ability to patrol shallow waters near coastlines, and can leap out to attack victims on dry land.