The zombie is the most common enemy in the game, the poor residents of the mansion who became infected with the T-Virus and left to rot in the dusty hallways. From the many different diaries and journals found, it is clear that they suffer greatly before the virus takes their life, and finally their soul.

The zombies in this game are more determined to end your life, even following you through doors. Ending their life isn't enough either, unless you decapitate them or incinerate them, they will slowly mutate into Crimson Heads.

The zombie is an easy enemy, as long as they're in small numbers. The Handgun is enough to keep them at bay. It's possible to decapitate one or many zombies with a single shotgun blast, simply aim up when they come into grabbing range, and fire.

However unlike the other games, a decapitation is guaranteed with this method.

Crimson Head

If a Zombie is killed but not properly disposed of (i.e. it was not decapitated or had its remains burnt using the Fuel Canteen filled with Kerosene and lit using the Lighter), it will later reanimate as one of these terrifying monsters.

These crimson-coloured creatures are the theorized stage of mutation between a Zombie and a Licker. It has razor sharp claws and is capable of running just as fast as you. It doesn't take a long time for a zombie to become "reborn" as a Crimson Head, so it is in your best interests to properly dispose of certain zombies you choose to kill, or face the consequences later on.

Crimson Head Prototype 1

This is the first recorded incident of a Zombie transforming into a Crimson Head, and as such is was locked away for further experimentation.

Its time in isolation obviously caused it to undergo further mutation, as this monster is much stronger than its counterparts, and can sustain a lot more damage before it is well and truly dead.


Cerberus, essentially a doberman infected with the T-Virus, is a fairly common enemy in the game. Despite the rotting skin and muscle hanging off their bones, they're still surprisingly quick, the virus giving these creatures an insane lust for blood. They'll dive for your arm the first chance they get.

Compared to the original game, these dogs are much harder to keep at bay. No more will a simple shot from the handgun keep them from advancing, now it takes two or three to knock them off their feet. If you do this a few times though they'll soon stay down for good.


Larger and more aggressive than normal, these birds will sit patiently unless they consider you a threat. It seems these crows feasted on a corpse infected with the virus, and driven them to act like something out of an Alfred Hitchcock novel.

You won't encounter crows very often during the game. Its better just to avoid them, however if you do want to take them down, don't use anything larger than the Handgun.

Fountain Plant

Although immobile and not much of a threat, you will at some point have to dispose of this overgrown garden weed. When you approach it will lash out with its whipping vines causing minor damage.

However, there is actually no need to get this close, as by using the Herbicide on the nearby water pump, this will destroy this plant and allow you to get past safely.

Forest Speyer

Forest Speyer, once a proud member of Bravo Team, is now one of the living dead. Based on his injuries, he was pecked to death by Crows infected with the T-Virus.

Shortly after finding his body he will spring to life and come after you. He will behave similar to an ordinary Zombie, however he will move much faster and his bites are more damaging. Put your former team member to rest as soon as possible.


Other appearances Resident Evil
A snake of gigantic proportions. This terrible demon is one of the first boss fights you encounter in the game, and it takes a large amount of ammunition to scare it away.

You have to be careful though, as not only does this snake cause massive amounts of damage, its fangs are dripping with a poison that cannot be cured with an ordinary Blue Herb. If you do get poisoned, you need special Serum to remedy it. On the second encounter, however, it has somehow lost its ability to poison you, so you just need to focus on keeping your health up and unloading everything you have into it.

Lisa Trevor

The story of Lisa Trevor is a sad one. You can read all about it in the Family Picture & Notes file, which describes the architect of the mansion George Trevor, his wife Jessica and their daughter Lisa being held prisoner by Umbrella and being experimented on with the T-Virus. Lisa is the sole survivor, however the multiple viruses on her body has turned her into a hideous practically indestructible monster. She now roams the mansion grounds looking for her family.

Great caution should be taken when you encounter Lisa Trevor. The manacles she wears she uses as a weapon, and it doesn't take many strikes to kill you. After enough ammunition has been unloaded into her body she will collapse, but the battle is not over. Take this opportunity to run for it, otherwise you will literally be there all day.


Other appearances Resident Evil
Small in comparison to the one you encounter earlier on, these pests are poisonous, and can hinder your progress when the need for a Blue Herb arises.

Although small, these should be avoided. Since you only encounter them a few times during the game, you shouldn't bother wasting any ammunition on these.


Other appearances Resident Evil
An ordinary bee that has been infected with the T-Virus and subsequently grown to roughly four times its original size. These insects are now more deadly than ever, being able to deliver a much more potent poison with its stinger. If you ever find yourself in a swarm, don't waste any ammunition on them, just run like hell.


Code name FI-03
Other appearances Resident Evil
Neptune is the code name for an experiment involving administering the T-Virus to an ordinary Great White shark. The result is a much larger, much more ferocious predator.

When you explore the Aqua Ring it is far easier and safer to simply run as fast as you can to the Control Room, as any one of the Neptune's can and will take a bite out of you given a chance. Once the room has been drained of its water the sharks will appear dead, however the largest of the three is still very much alive. Whatever you do, don't step into the water, instead push the generator into the water and watch the big fish fry.

Plant 42

Other appearances Resident Evil
This huge monstrous bulb is the product of the researchers in the Guardhouse Residence experimenting with the T-Virus on plants. The result of which is a carnivorous plant that feeds on the blood of its victims. It is said that this plant grew this large by feeding off the contaminated water from the broken water tank in the basement.

These exposed roots also hold the key to defeating it, as by concocting the V-JOLT compound you are able to administer this to the plant via its roots, severely weakening it and making the battle against it a little easier. If you're playing as Jill then the Grenade Launcher with the Incendiary Shells are the preferred choice of weapon. If you're playing as Chris you only have the Shotgun, but if you used the V-JOLT then it will be enough to defeat it.


Code name MA-121
Other appearances Resident Evil
Resident Evil Survivor
Resident Evil Zero
An extremely powerful creature with claws on all four limbs, and the ability to jump several metres in the air. Encountered later on in the game, these creatures replace the zombie as being the most common enemy, but thankfully for a limited time only.

These frog-like creatures are very dangerous; they have two different forms of attack. They either swipe at your legs, or jump and slash at your torso, which if they're close enough could go right over your head and result in decapitation. Using the Shotgun or Magnum Revolver when playing as Chris, or the Grenade Launcher with Acid Shells as Jill, is the best way to deal with these.

Web Spinner

Other appearances Resident Evil
An enormous spider created by experimenting with the T-Virus on arachnids.

These venomous eight-legged monsters can surprise you when they suddenly land in front of you with their ability to walk on walls and ceilings, but their presence within a room can be known to you if you listen out for their low-bass thumping noise as the scurry around. Use the Shotgun or the Grenade Launcher to bring them down.

Black Tiger

The mother of all spiders, this is a larger variation of the Web Spinner. This giant spider has more strength, speed and spitting range than its smaller companions.

Although big and menacing, this boss can be defeated quite easily. By either using the Grenade Launcher loaded with Acid Shells or Incendiary Shells, or even just the Shotgun, it will only take a few shots to bring down.


Other appearances Resident Evil
The term chimera is used when an organism consists of two or more different genetic tissues. This creature is the combination of human DNA and that of a fly, resulting in a deadly monster of grotesque appearance but severely lacking in intelligence.

These creatures like to hang around in small dark places, such as air ducts. This means that they will not be immediately visible when entering a location, but will pounce into the room when you pass close to one of their hideaways.


Code name T-002
Other appearances Resident Evil
The world's most powerful biological weapon. The Tyrant has the build of a large man, with a cluster of claws on its left forearm instead of a hand. Its heart is located outside its body on its chest, however this still doesn't make it vulnerable for attack or weakness.

Dealing with the Tyrant the first time round is fairly easy, all he will do is follow you around the Laboratory in a casual manner. Use the Magnum or the Grenade Launcher for this battle. If you get within a certain distance, he will start swiping his claw at you, which can hurt a lot.

The second battle takes place on the Heliport, and there's no need to fire at him. Keep avoiding him until the countdown timer reaches a dangerously low level, and Brad will drop something to help you defeat Tyrant.